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| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Allopurinol | BW-56-158; ATH-008; NSC-1390 | Approved | Sebela Ireland Ltd | Lopurin, Zyloric, Zyloprim, 路必利 | United States | Gout; Hyperuricemia | Casper Pharma Llc | 1966-08-19 | Hand-Foot Syndrome; Hyperuricemia; Diabetes Mellitus, Type 2; Liver Cirrhosis; Fibrosis; Nephrolithiasis; Angina Pectoris; Gout; Renal Insufficiency, Chronic; Inflammation | Details |
| Febuxostat | TMX-67; TEI-6720; TMX-67XR | Approved | Teijin Pharma | 风定宁, Uloric, 优立通, Adenuric, Febric, 瑞扬, Feburic, Febutaz | EU | Gout | Menarini International Operations Luxembourg Sa | 2008-04-21 | Hyperuricemia; Kidney Calculi; Pain; Kidney Diseases; Tumor Lysis Syndrome; Hypertension; Angina Pectoris; Cardiovascular Diseases; Gout | Details |
| Allopurinol sodium | Approved | Mylan Nv | Aloprim | United States | Gout; Hyperuricemia | Mylan Institutional Inc | 1996-05-17 | Hyperuricemia; Gout; Leishmaniasis | Details | |
| Allopurinol/Benzbromarone | Approved | Hyperuricemia | Details | |||||||
| Topiroxostat | FYX-051; SK-0910 | Approved | Fuji Yakuhin Co Ltd | Uriadec, Topiloric | Japan | Gout; Hyperuricemia | Fuji Yakuhin Co Ltd, Sanwa Kagaku Kenkyusho Co Ltd | 2013-06-28 | Hyperuricemia; Diabetic Nephropathies; Gout | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Tigulixostat | LC-350189; IBI-350; LR-19074 | Phase 3 Clinical | Lg Life Sciences Ltd | Hyperuricemia; Heart Diseases; Gout | Details |
| Oxipurinol （XORTX Therapeutics） | XRx-008; XRx-101 | Phase 2 Clinical | Xortx Therapeutics | Polycystic Kidney Diseases | Details |
| THDBH-151 | THDBH151; THDBH-151 | Phase 2 Clinical | Dongbao Zixing (Hangzhou) Biological Medicine Co Ltd | Gout | Details |
| TMX-049 | TMX-049; TMX-049DN | Phase 2 Clinical | Teijin Pharma | Diabetic Nephropathies | Details |
| Xrx-221 | Phase 1 Clinical | Xortx Therapeutics | Diabetic Nephropathies | Details | |
| IBI-128 | IBI128; IBI-128 | Phase 1 Clinical | Innovent Biologics(Suzhou) Co Ltd | Hyperuricemia; Arthritis, Gouty; Metabolic Diseases; Gout | Details |
| HZN-457 | HZN-457 | Phase 1 Clinical | Horizon Therapeutics Ireland Dac | Details |
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